23 Mar 2026 · 2 h 29 min
Books from David Sinclair
“David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!”
2 books mentioned
Buy links are Amazon affiliate links. Timestamps come from the audio release (which includes ad breaks), so the video may differ by a few minutes.
The conversation
Harvard geneticist David Sinclair discusses his research on reversing aging, including the information theory of aging and clinical trials to restore eyesight. He explains how fasting, supplements, and gene therapy may reset biological age and treat age-related diseases.
Talking points
- Personal motivation from childhood poem
- Information theory of aging explained
- Role of sirtuins and NAD in repair
- Fasting as hormetic stressor for longevity
- Supplements: NMN, resveratrol, spermidine
- Gene therapy to reverse blindness
- Possibility of simulation universe and AI risks

