An unofficial reader's index — not affiliated with The Diary of a CEO or Steven Bartlett.

23 Mar 2026 · 2 h 29 min

Books from David Sinclair

“David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!”

2 books mentioned

  1. Cover of Lifespan
    Guest's book

    Lifespan

    by David Sinclair

    David Sinclair · ~00:03:02 · on 2 episodes

    Buy on Amazon
  2. Cover of Now We Are Six
    Mentioned

    Now We Are Six

    by A. A. Milne

    David Sinclair · ~00:03:02

    Buy on Amazon

Buy links are Amazon affiliate links. Timestamps come from the audio release (which includes ad breaks), so the video may differ by a few minutes.

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The conversation

Harvard geneticist David Sinclair discusses his research on reversing aging, including the information theory of aging and clinical trials to restore eyesight. He explains how fasting, supplements, and gene therapy may reset biological age and treat age-related diseases.

Talking points

  • Personal motivation from childhood poem
  • Information theory of aging explained
  • Role of sirtuins and NAD in repair
  • Fasting as hormetic stressor for longevity
  • Supplements: NMN, resveratrol, spermidine
  • Gene therapy to reverse blindness
  • Possibility of simulation universe and AI risks